Mito-nuclear interactions modify Drosophila exercise performance
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چکیده
منابع مشابه
Factors affecting mito-nuclear codon usage interactions in the OXPHOS system of Drosophila melanogaster.
Codon usage bias varies considerably among genomes and even within the genes of the same genome. In eukaryotic organisms, energy production in the form of oxidative phosphorylation (OXPHOS) is the only process under control of both nuclear and mitochondrial genomes. Although factors affecting codon usage in a single genome have been studied, this has not occurred when both interactional genomes...
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The assembly and function of mitochondria require coordinated expression from two distinct genomes, the mitochondrial DNA (mtDNA) and nuclear DNA (nDNA). Mutations in either genome can be a source of phenotypic variation, yet their coexpression has been largely overlooked as a source of variation, particularly in the emerging paradigm of mitochondrial replacement therapy. Here we tested how the...
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ژورنال
عنوان ژورنال: Mitochondrion
سال: 2019
ISSN: 1567-7249
DOI: 10.1016/j.mito.2018.11.005